This kit includes:
- Saliva DNA collection kit (other collection methods can be requested)
- Enhanced Human Whole-Exome Sequencing (WES)
- Mitochondrial Whole-Genome Sequencing (mtWGS)
- Genetic data harmonized specifically for use with GeneSavvy’s analysis, reporting, and research tools
- Downloadable raw genetic data files (By request, we can provide your raw data in standard genetic file formats)
- GeneSavvy Variant Exploration Report (see details below)
The Variant Exploration Report that comes with the starter kit includes:
- All Genetic Variants found by our Enhanced Human Whole-Exome Sequencing (WES)
- All Genetic Variants found by our Mitochondrial Whole-Genome Sequencing (mtWGS)
- Genotyping data and SNPs curated for functional medicine practitioners
- HLA Subtypes found (Human Leukocyte Antigens)
- KIR Subtypes found (Killer-cell Immunoglobulin-like Receptors)
- RCCX gene module information
- And more**
**We are continuously pioneering new analysis tools to help identify functional genetic patterns between disease-associated rare variants, lifestyle-changing polymorphisms, real-time protein/enzyme activity, and environmental-genetic interactions among other insights. Many of these tools can be used to enhance your GeneSavvy reports by adding additional information to them without the need to collect and process new saliva samples.
Technical Information:
Our testing was designed to sequence the exons and canonical splice sites (+/1,2) of the whole exome
including extra coverage on genes and intron locations associated with medical disorders and treatment options. GeneSavvy has
developed highly advanced protocols to target and extract variants and genetic features in exonic regions, intronic regions
of interest, splice sites, and untranslated gene regions of interest with the following technical
specifications:
- 45x Depth of Coverage for Target Regions
- 100x Depth of Coverage for Mitochondrial Regions
- Specificity >99%
- Sensitivity >96%