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In: Thyroid

Genetic Influence on Thyroid Stability Many people suffer the effects of thyroid disease which include hypothyroidism, hyperthyroidism, Grave’s disease, Hashimoto’s thyroiditis (autoimmune thyroiditis), generalized thyroid inflammation and thyroid cancer. Unrelated human subjects share 99.9% of their genome. It has been estimated that 90% of the remaining variation is accounted for by approximately 10 million common single nucleotide polymorphisms (SNPs), single base changes spread throughout the genome. These are very useful in studying gene-phenotype associations as they occur commonly in the general population, and may either cause changes in gene function themselves, or more frequently are markers of nearby elements that...