Nutritional and Metabolic Gene Status With Autism Versus Neurotypical Children and the Association with Autism Severity   Introduction Current research demonstrated a strong relationship between the genes that control nutrition and metabolic function that manifest as early childhood developmental disorders. Studies reveal low levels of biotin, plasma glutathione, RBC SAMe, plasma uridine, plasma ATP, RBC NADH, RBC NADPH, CoQ10, plasma sulfate, plasma tryptophan, dopamine, glutathione, high level of oxidative stress markers and plasma glutamate. https://doi.org/10.1186/1743-7075-8-34   Genes Implicated There are many implicated genes in Autism and Neurotypical children that demonstrate possible pathway disturbances that involve key functional proteins and enzymes...

Mitochondria are the energy producers of human cells. The energy currency for the work that is required to power up metabolism by producing the energy-rich molecule adenosine triphosphate (ATP). The ATP is produced in the mitochondria using energy stored in the food that is consumed. These ATP's are essential in keeping every step of metabolism in equilibrium which in turn effects every system of the human body including immunity, detoxification, hormones, brain neurotransmitters, etc. Genetic testing to determine metabolic efficiency in chronic health concerns is essential. Also essential in conditions like OCD, ADHD, ASD (Autism), Fatigue, Immune Related Fatigue, Chronic...

There are hundreds of mitochondria within human cells and it is crucial to protect the mitochondria from age-related stress and oxidative burden in order to prevent functional disease and aging risk. These mitochondria are power generators that are responsible for the cell grid. If they are compromised the functional performance survival of the cell is jeopardized complete loss can result. Each mitochondria carries its own small circular DNA genome, called mtDNA, the products of which are required for energy production. Because mtDNA has limited repair abilities, normal and mutant versions of mtDNA are often found in the same cell, a condition...

New gene discoveries that code for neuronal connectivity are beginning to give new hope in targeting therapy to address the problems associated with connectivity. The autism spectrum brain exhibits connectivity disturbances that alters communication between neuronal regions. Neuronal mitochondrial depletion is among the causative factors that create impaired connectivity and synaptic control. There are many genes implicated in this phenomenon. Genes Studied In ASD http://www.genecards.org/Search/Keyword… Research Article Links https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691066/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420970/

Autism symptoms can be aggravated by inflammatory activity, chronic sensitivity and neurotransmitter trafficking. There are a variety of combination of therapeutically effective agents in personalized treatment. Some Guidelines 1. Disodium cromoglycate (Gastrocrom) ‘Mast cell stabilizer’ 100 – 400 mg/day dissolved in water 2. Cyproheptadine (Periactin) Serotonin and histamine-1receptor antagonist 1 – 4 mg/day 3. Ketotifen (Zaditen) Histamine-1receptor antagonist, anti-eosinophil 1 – 4 mg/day 4. Rupatadine (Rupafin) Histamine-1 receptor and platelet activating factor antagonist; mast cell inhibitor, anti-eosinophil 20 mg/day 5. NeuroProtek Contains flavonoids and a proteoglycan Two capsules/20 kg body weight/day and Nrf2 as additional item 6. Black Seed Oil...