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In: Mitochondrial

Mitochondria are the energy producers of human cells. The energy currency for the work that is required to power up metabolism by producing the energy-rich molecule adenosine triphosphate (ATP). The ATP is produced in the mitochondria using energy stored in the food that is consumed.

These ATP’s are essential in keeping every step of metabolism in equilibrium which in turn effects every system of the human body including immunity, detoxification, hormones, brain neurotransmitters, etc.

Genetic testing to determine metabolic efficiency in chronic health concerns is essential. Also essential in conditions like OCD, ADHD, ASD (Autism), Fatigue, Immune Related Fatigue, Chronic Infections, etc

Genetic genotyping and phenotyping assist in identifying key characteristics that involve mitochondrial health. Genetic analysis and action can assist in providing answers and remedy for these concerns.

There are hundreds of mitochondria within human cells and it is crucial to protect the mitochondria from age-related stress and oxidative burden in order to prevent functional disease and aging risk. These mitochondria are power generators that are responsible for the cell grid. If they are compromised the functional performance survival of the cell is jeopardized complete loss can result.

Each mitochondria carries its own small circular DNA genome, called mtDNA, the products of which are required for energy production. Because mtDNA has limited repair abilities, normal and mutant versions of mtDNA are often found in the same cell, a condition known as heteroplasmy. Most people start off life with some level of heteroplasmy, and the levels of mutant mtDNA increase throughout life. When a critical threshold level of mutant mtDNA is passed, cells become nonfunctional or die.

When mitochondria mutant mtDNA is critical a process of mitophagy results. The important goal in targeting mitochondria is to prevent it from getting to the point of no return.

It is essential that thorough assessment be made through genetic analysis that specifically assess mtDNA and corresponding gene controls.

Many health conditions are caused by critical mutant mtDNA including neurodegenerative disease, Autism, Autism Spectrum Disorder, Disorders of Autonomic Control, Schizophrenia, Behavioral Disorders like OCD, ADHD, Metabolic and Gating Disturbances, Chronic Immune Functional Related Fatigue, Chronic Pain Syndrome, etc.

GeneSavvy testing is the best form of analysis for these disorders and should be the first place in working up the foundational causes and needed targeting to address the functional disturbances caused by mutant mtDNA and nuclear mitochondrial gene disturbances.

We have analyzed over 2000 genetic results and can affirm that foundational genetic analysis will dramatically inflence treatment targeting and outcomes.

 

http://www.sciencedirect.com/science/article/pii/S0005272815001097