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October 2017

Nutritional and Metabolic Gene Status With Autism Versus Neurotypical Children and the Association with Autism Severity   Introduction Current research demonstrated a strong relationship between the genes that control nutrition and metabolic function that manifest as early childhood developmental disorders. Studies reveal low levels of biotin, plasma glutathione, RBC SAMe, plasma uridine, plasma ATP, RBC NADH, RBC NADPH, CoQ10, plasma sulfate, plasma tryptophan, dopamine, glutathione, high level of oxidative stress markers and plasma glutamate. https://doi.org/10.1186/1743-7075-8-34   Genes Implicated There are many implicated genes in Autism and Neurotypical children that demonstrate possible pathway disturbances that involve key functional proteins and enzymes...
Expressed Phenotype and Epigenetic Reprogramming Phenotype An individual's phenotype consists of the traits we can observe. These can include features of appearance, behavior, metabolism, immunity or anything else we can detect. Collectively, genes make up the observable phenotype. The phenotype expression can be influenced by a variety of factors and generational implications. [1] Phenotype Expression The phenotype is also known as the clinical expression of a specific disease. For instance, in cases of neurodevelopment disorders, Autism is an expression of the phenotype. In inherited familial high cholesterol, the expressions of the genes that control this metabolism are the phenotypes. Phenotypic abnormalities can...