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August 2017

August 16, 2017

GeneSavvy Press Release

For Immediate Release: 7/26/17


GeneSavvy Announces Launch in Emerging Wellness as a Service (WaaS) Industry


Former Courtagen Employees to Team Up with GeneSavvy



GeneSavvy, a division of HealthSavvy, Inc. based in Kenmore, WA announces their launch into the emerging Wellness as a Service industry with genome-centric biotechnology built to promote vibrant health through their proprietary decision management software. GeneSavvy Co-Founder and CEO Kris Fobes has been developing GeneSavvy’s intelligent clinical decision platform since 2012 with the launch of subsidiary company, HealthCoach7. HealthCoach7 is a genetic health company focused on developing and providing diagnostics and treatments for children with ASD, developmental delay, and other complex pediatric and adult disorders with successful treatment outcomes worldwide.


After hosting the Hyper Wellbeing Summit, Hyper Wellbeing Founder Lee Dryburgh coined the Wellness as a Service (WaaS) model as a way to describe the future of healthcare technology using big data and new technology to empower people to live longer, healthier lives through disease prevention rather than illness reaction. GeneSavvy has been developed over the last 5 years to do exactly that. GeneSavvy leverages biodata to make predictive suggestions that will be scientifically proven to prevent disease, prolong vibrant life, and assist clinical decisions in complex disease cases.


Several former Courtagen employees have teamed up with GeneSavvy including former Chief Medical Officer and Genetic Researcher, Dr. Richard G. Boles after Courtagen Life Sciences announced the closure of their medical genetic company on July 18th 2017. Courtagen shut down their medical genetic company to pursue research in genomic cannabis through their subsidiary company, Medicinal Genomics Corporation. The closure of Courtagen has left thousands of doctors and even more families in need of a company that can offer similar services. With GeneSavvy’s technology and a few of Courtagen’s former brilliant minds, GeneSavvy is well positioned to fill that void and provide the services those medical professionals and families need.


GeneSavvy will be accepting genetic testing orders starting in August 2017 through our websites Our genetic testing panels will be sequenced using Illumina’s Next Generation Sequencing Technology and processed through GeneSavvy’s proprietary bioinformatics pipeline and report software. Our proprietary bioinformatics pipeline and reporting software will be built in collaboration with several pioneers in Functional Genetics to be an extremely comprehensive and actionable system for ASD, developmental delay, and other complex pediatric neurological disorders. Actionable genetic reports for chronic regional pain disorders, mitochondrial and metabolic disorders, epilepsy and seizure disorders and other complex disorders will be available soon after.


GeneSavvy is currently offering several genetic panels, including the NeuroDevGS panel which is an extremely comprehensive panel to cover genes involved in Autism Spectrum, Developmental Delay, and other Complex Neurological Disorders. Another comprehensive test offered by GeneSavvy is their LongevityGS panel. This panel was built to bring next generation sequencing technology to the genes looked at by some of leaders in functional medicine for holistic health. GeneSavvy also covers Whole Exome genetic testing through their PowerXomeGS panel. If you’re looking for one of the most comprehensive genetic tests available in the market, the PowerXomeGS would be a great place to start. All of GeneSavvy’s genetic tests will be ordered by physicians. If you don’t have a physician for your genetic needs, we can connect you with one to complete your order. 




UPDATE: 8/15/17

**Due to the amount of inquiries and demand we received after announcing our services, we had to get something online quickly to accept orders. Our website is currently up and accepting orders but the website content is far from complete. will be adding and updating content and features to the website over the next few weeks/months/forever… All of our panels will come with our GeneSavvy Guarantee of Action. No matter what panel you order, we will guarantee there will be health action to take. We define health action as current phenotype treatment, future risk assessment and prevention, nutritional support for pathway inefficiencies, or any other action items added to your health protocol because of our panels.



GeneSavvy will be offering exclusive discounts on genetic testing for previous Courtagen customers and for new customers that are part of our first 1000 orders. Send us an email at [email protected] if your interested in getting discounted genetic tests.

Mitochondria are the energy producers of human cells. The energy currency for the work that is required to power up metabolism by producing the energy-rich molecule adenosine triphosphate (ATP). The ATP is produced in the mitochondria using energy stored in the food that is consumed.

These ATP’s are essential in keeping every step of metabolism in equilibrium which in turn effects every system of the human body including immunity, detoxification, hormones, brain neurotransmitters, etc.

Genetic testing to determine metabolic efficiency in chronic health concerns is essential. Also essential in conditions like OCD, ADHD, ASD (Autism), Fatigue, Immune Related Fatigue, Chronic Infections, etc

Genetic genotyping and phenotyping assist in identifying key characteristics that involve mitochondrial health. Genetic analysis and action can assist in providing answers and remedy for these concerns.

There are hundreds of mitochondria within human cells and it is crucial to protect the mitochondria from age-related stress and oxidative burden in order to prevent functional disease and aging risk. These mitochondria are power generators that are responsible for the cell grid. If they are compromised the functional performance survival of the cell is jeopardized complete loss can result.

Each mitochondria carries its own small circular DNA genome, called mtDNA, the products of which are required for energy production. Because mtDNA has limited repair abilities, normal and mutant versions of mtDNA are often found in the same cell, a condition known as heteroplasmy. Most people start off life with some level of heteroplasmy, and the levels of mutant mtDNA increase throughout life. When a critical threshold level of mutant mtDNA is passed, cells become nonfunctional or die.

When mitochondria mutant mtDNA is critical a process of mitophagy results. The important goal in targeting mitochondria is to prevent it from getting to the point of no return.

It is essential that thorough assessment be made through genetic analysis that specifically assess mtDNA and corresponding gene controls.

Many health conditions are caused by critical mutant mtDNA including neurodegenerative disease, Autism, Autism Spectrum Disorder, Disorders of Autonomic Control, Schizophrenia, Behavioral Disorders like OCD, ADHD, Metabolic and Gating Disturbances, Chronic Immune Functional Related Fatigue, Chronic Pain Syndrome, etc.

GeneSavvy testing is the best form of analysis for these disorders and should be the first place in working up the foundational causes and needed targeting to address the functional disturbances caused by mutant mtDNA and nuclear mitochondrial gene disturbances.

We have analyzed over 2000 genetic results and can affirm that foundational genetic analysis will dramatically inflence treatment targeting and outcomes.

August 8, 2017

Autism and Connectivity

New gene discoveries that code for neuronal connectivity are beginning to give new hope in targeting therapy to address the problems associated with connectivity. The autism spectrum brain exhibits connectivity disturbances that alters communication between neuronal regions. Neuronal mitochondrial depletion is among the causative factors that create impaired connectivity and synaptic control. There are many genes implicated in this phenomenon.

Genes Studied In ASD…

Research Article Links

Autism symptoms can be aggravated by inflammatory activity, chronic sensitivity and neurotransmitter trafficking. There are a variety of combination of therapeutically effective agents in personalized treatment.

Some Guidelines

1. Disodium cromoglycate (Gastrocrom)
‘Mast cell stabilizer’ 100 – 400 mg/day dissolved in water

2. Cyproheptadine (Periactin) Serotonin and histamine-1receptor antagonist
1 – 4 mg/day

3. Ketotifen (Zaditen) Histamine-1receptor antagonist, anti-eosinophil 1 – 4 mg/day

4. Rupatadine (Rupafin) Histamine-1 receptor and platelet activating factor antagonist; mast cell inhibitor, anti-eosinophil 20 mg/day

5. NeuroProtek Contains flavonoids and a proteoglycan Two capsules/20 kg body weight/day and Nrf2 as additional item

6. Black Seed Oil 1 tsp 2x day
7. Autoimmune Paleo Dietary Focus
8. Oxytocin Sublingual cycled (Dopamine)
9. SAMe sublingual cycled (Dopamime)
10. CoQ10 mouth spray
11. NAD+ mouth spray
12. Sublingual biotin and folinate
13. Stem cell therapy as option
14. Hyperbaric therapy
15. Immunotherapy
16. Low Dose Naltrexone

*Doses will vary depending on age and weight of patient.

Other Considerations:
1. Carbohydrate (starch splitting) enzyme repletion
2. Human Breast Milk Derived Probiotic Culture
3. Fecal Implantation healthy donor
4. Antimicrobial eradication in complicated cases

Additional Testing Considerations:
1. Folate Receptor Antibody (FRAT)
2. Cunningham Panel (PANS / PANDAS)…/

Personalized genetics are indeed, personal, powerful, revealing, and relating to an individual’s wellness and longevity. Next generation sequencing and whole exome technology has allowed for the complete capture of the entire human genome.

We have worked with countless numbers of adults and children with complex diseases including autism, neurological development disorders, immunological disorders, metabolic disorders and rare disease with successful cases all over the world. 

Genetic testing is the foundation of discovering more exact diagnostic testing and treatable actions. Tens of thousands of dollars can be saved by discovering the genes and associated pathways before running costly lab testing. Treatment then is more targeted and effective also saving costly dollars in medications and supplements.

GeneSavvy architects this foundation of targeted diagnosis and treatment in a personalized manner through our comprehensive genetic panels and proprietary bioinformatics pipeline.