Background

GeneSavvy was built for functional health practitioners, the most fierce warrior moms, and the most advanced biohacking geeks who want a more advanced genetic testing and reporting platform for true precision medicine.

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UNDERSTANDING THE WILD, WILD WEST

Lingo and catch-phrases in genetics can make it tricky to compare labs and services. Here’s a quick rundown of the basics you should know to make decisions about lab testing and analysis reports, in friendly metaphors and plain English so you can better understand what’s going on with clinician and consumer-facing genetics in 2020: SNP Genotyping versus Phenotyping, Exons and Introns, depth/confidence, and naming conventions. We want you to be able to ask the right questions! READ THE POST

GeneSavvy is the most advanced and clinically actionable genetic testing and reporting platform in functional medicine:

NOT JUST ANOTHER SNP TEST: it’s time to take your genetic testing to the next level

There is so much more actionable data that genetic testing can provide beyond genotyping for common SNPs. GeneSavvy has developed advanced bioinformatics technologies and processes so that we can provide you with as much actionable and interesting genetic information as possible from a single test! Our GeneSavvy Starter Kit Test includes information about:

  • Human whole exome sequencing
  • Mitochondrial genome sequencing
  • Genotyping and SNPs
  • HLA Subtyping (Human Leukocyte Antigens)
  • KIR Subtyping (Killer-cell Immunoglobulin-like Receptors)
  • RCCX gene module information
  • And more!

We are also constantly developing new technologies to help you explore your GeneSavvy genetic data in new ways and to make more use of your genetic data.

FUNCTIONAL DATA ENRICHMENT: we connect the dots

Data enrichment is all about creating more powerful insights into data through associations. We’ve built our own custom enrichment database that is full of clinical actionability for functional health practitioners.

We are constantly adding new information to our databases, providing new insights into gene/variant associations with health-related pathways, cellular & molecular functions, lab biomarkers, interactions with pharmaceuticals, food/nutrients, environmental factors, vitamins/herbs, and MORE. Our roots are in functional medicine, so our enrichment data is geared around terms that functional health practitioners can easily use to guide action.

*Not all genes/variants are currently enriched by our database. Our database will continue to grow as research continues.

DIAGNOSTIC GRADE DATA: higher quality and higher accuracy for more confident clinical integrations

Quality:
The GeneSavvy difference starts with our lab. We use top of the line lab equipment like Illumina’s NovaSeq 6000 machines, combined with stringent quality control parameters that constantly exceed manufacturer specifications for reproducible and accurate results.

Depth of confidence:
When you get your genetic test through GeneSavvy, you’re getting a depth of confidence far superior to other genetic tests. Genetic sequencing machines split open cells to read billions of points of data, some of which will inevitably come from a cell with damaged DNA that isn’t representative of your overall body. To combat this, we read each location many times from many different cells. Instead of reading these data points once or twice (like many consumer genetic testing companies), we read these points an average of 25-75 times (sometimes even thousands of times). This enables us to be confident the data is accurate and not just some environmental damage to a particular cell from your recent hop through an airport X-ray.

Breadth:
One of the biggest reasons we started GeneSavvy was because we wanted to build a system that gave us access to MORE data. A lot of the genetic information used in the health industry comes HEAVILY filtered to us. Sometimes it is filtered for good reasons, such as removing misaligned data that could lead to false positive associations. Most of the time however, filtering is done to “protect” us from seeing data that someone determined unneccessary, difficult to comprehend, or useless for the specific application they expect. We filter out data that doesnt pass our quality standards, but we strive to keep as much of your data as possible available to access, research, and include in your health provider’s hypothesis if there is a potential correlation to explore.

GENES WORK TOGETHER, not in isolation

Many genetic testing and reporting services use oversimplified correlation data to associate one gene with one phenotype. That approach completely ignores the complex interactions between genes and gives at best an incomplete, and often inaccurate, understanding of your genetics! We work hard to take upstream, downstream, and co-factor interactions into consideration when looking at how genes contribute to our health concerns. We build comprehensive genetic networks surrounding diseases, biological functions, and more to help identify possible targets for clinical action.

TRUE PERSONALIZED MEDICINE: we listen to the unique story in your genes

Our platform was built to help functional health practitioners utilize millions of biodata points to design the ultimate patient-centered, personalized, and effective treatment plans for every patient.

We aim to help practitioners identify patient-specific root mechanisms of complex disease quickly (and with less guesswork) by identifying genetic variants with the highest potential to cause negative impact. By reducing the time to uncover and identify these unique mechanisms and interactions, our testing platform will reduce overall patient costs, improve patient engagement, and empower the patient with a proactive personalized plan that promotes optimal health and longevity.

INSATIABLE CURIOSITY: we want answers to YOUR questions

Our most valuable asset is our persistent curiosity that drives our efforts to find answers when nobody else can or will. The challenges that are most frustrating to others following a traditional model are the ones most exciting in our paradigm. In our neverending quest to solve the genetic puzzle, we work with a diverse group of advisors, panel curators, and experts that ensure we utilize well-rounded research, clinical tools, and other actionable genetic associations without bias toward one modality or another.

GeneSavvy Starter Kit

Get started on the most advanced and clinically actionable genetic platform in functional medicine with our simple saliva collection kit that can be used from the comfort of your own home!

Once we receive your sample, we will utilize the massive clinical power of Next Generation Sequencing (NGS) technology to extract your unique genetic information. Once our customized lab processing is complete, we will send you a GeneSavvy Variant Exploration report that can be shared with your functional medicine team to develop more personalized and more effective health and lifestyle recommendations.
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GeneSavvy Variant Exploration Report

This report is included free with the purchase of our GeneSavvy Starter Kit, but if you already have raw genetic data from another testing company, this service is for you!

Many other genetic testing companies offer to provide a copy of your raw genetic data in the form of a VCF or TXT file. We can re-evaluate that raw data in our system to provide more clinically-actionable information for your functional medicine team. We won’t be able to provide you the full set of data that our GeneSavvy Starter Kit provides if we don’t have everything our lab extracts, but we can help you get more mileage out of your existing data.

Convert your raw genetic data into clinically-actionable information by purchasing this service, then following the simple upload instructions we email to you.

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